If HPA axis suppression is noted, an attempt should be made to gradually withdraw the drug, to reduce the frequency of application, or to substitute a less potent corticosteroid. The results show that the drug caused a slight lowering of adrenal corticosteroid secretion. In a study evaluating the effects of mometasone furoate cream on the HPA axis, 15 grams were applied twice daily for 7 days to six adult subjects with psoriasis or atopic dermatitis. This may be done by using the adrenocorticotropic hormone (ACTH) stimulation test. Because of the potential for systemic absorption, use of topical corticosteroids may require that patients be periodically evaluated for HPA axis suppression. Factors that predispose a patient using a topical corticosteroid to HPA axis suppression include the use of high-potency steroids, large treatment surface areas, prolonged use, use of occlusive dressings, altered skin barrier, liver failure and young age. Manifestations of Cushing’s syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on treatment. This may occur during treatment or after withdrawal of treatment. It is not for oral, ophthalmic, or intravaginal use.ĥ.1 Effects on Endocrine System Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency. Mometasone furoate cream, 0.1% is for topical use only. Avoid use on the face, groin, or axillae. Do not apply mometasone furoate cream, 0.1% in the diaper area if the patient still requires diapers or plastic pants, as these garments may constitute occlusive dressing. Do not use mometasone furoate cream, 0.1% with occlusive dressings unless directed by a physician. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary. Therapy should be discontinued when control is achieved. Since safety and efficacy of mometasone furoate cream, 0.1% have not been established in pediatric patients below 2 years of age use in this age group is not recommended. Mometasone furoate cream, 0.1% may be used in pediatric patients 2 years of age or older. Mometasone Cream Dosage and Administration Apply a thin film of mometasone furoate cream, 0.1% to the affected skin areas once daily. The information provided herein is supplied to the best of our abilities to make it accurate and reliable as it is published after a review by a team of professionals.2. Background: Topical steroids have been previously associated with potential for hyperglycemia and glucosuria, and thought to have a relatively safe side effect profile. This information is solely intended to provide a general overview on the product and must be used for informational purposes only. World Health Organization Classification of Topical Corticosteroids. Metaz 0.1 Cream belongs to a group of medicines called topical corticosteroids. You should not use the information provided herein to diagnose, prevent, or cure a health problem. The potency of a topical corticosteroid depends on the formulation, the specific molecule type, level of skin absorption, and amount that reaches the target cell. Potency is also increased when a formulation is used under occlusive dressing or in intertriginous areas. It is effective in treating skin conditions with inflammation and itching such as eczema, psoriasis, and dermatitis. Metaz 0.1 is a topical corticosteroid, prescribed for treatment of inflammatory skin disorders (such as eczema and psoriasis), allergic rhinitis (such as hay fever), and asthma. It works by reducing the actions of chemicals in the body that cause inflammation of the skin. Nasal spray is used for seasonal allergies like runny nose. It reduces inflammatory reactions and modifies immune reactions in the body. Nothing contained on this page is intended to create a doctor-patient relationship, replace or be a substitute for a registered medical practitioner's medical treatment/advice or consultation. The absence of any information or warning to any medicine shall not be considered and assumed as an implied assurance. We highly recommend that you consult your registered medical practitioner for all queries or doubts related to your medical condition. Metaz 0.1 Cream is neither an antifungal nor an antibiotic. You hereby agree that you shall not make any health or medical-related decision based in whole or in part on anything contained in the Site. It is a corticosteroid which is used to reduce inflammation (redness, swelling) in various conditions. It is available as an ointment, cream and lotion for external application. It is also available as a nasal spray or powder for inhalation. Metaz 0.1 Cream is effective for my child.
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